Kristina A Matkowskyj Selected Research

LY3023414

1/2022	PI3K/mTOR inhibition prevents anal cancer in mice with established low-grade anal dysplasia.
1/2017	Dual PI3K/mTOR Inhibition in Colorectal Cancers with APC and PIK3CA Mutations.

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Kristina A Matkowskyj Research Topics

Disease

34	Neoplasms (Cancer) 01/2022 - 08/2003
9	Colorectal Neoplasms (Colorectal Cancer) 01/2019 - 01/2007
7	Carcinogenesis 11/2019 - 11/2011
7	Colonic Neoplasms (Colon Cancer) 01/2019 - 08/2003
5	Anus Neoplasms (Anal Cancer) 01/2022 - 01/2016
4	Adenocarcinoma 01/2020 - 05/2012
2	Microsatellite Instability 01/2022 - 01/2020
2	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2021 - 11/2019
2	Infections 01/2021 - 01/2016
2	Neoplasm Metastasis (Metastasis) 01/2021 - 01/2007
2	Carcinoma (Carcinomatosis) 11/2019 - 01/2014
2	Hepatocellular Carcinoma (Hepatoma) 12/2017 - 04/2014
2	Ischemia 01/2016 - 01/2016
2	Necrosis 01/2016 - 01/2016
2	Polyps 01/2016 - 04/2013
2	Inflammation (Inflammations) 10/2012 - 07/2004
1	Neoplasms, Cystic, Mucinous, and Serous 10/2021
1	Squamous Intraepithelial Lesions 01/2021
1	Breast Neoplasms (Breast Cancer) 01/2021
1	Virus Diseases (Viral Diseases) 01/2021
1	Papillomavirus Infections 01/2021
1	Liver Neoplasms (Liver Cancer) 01/2021
1	Renal Cell Carcinoma (Grawitz Tumor) 03/2020
1	Polycystic liver disease 03/2020
1	Turcot syndrome 01/2020
1	Gastrointestinal Neoplasms (Gastrointestinal Cancer) 01/2020
1	Weight Loss (Weight Reduction) 01/2018
1	Hepatitis 01/2018
1	Insulin Resistance 01/2018
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2018
1	Reperfusion Injury 01/2016
1	Acquired Immunodeficiency Syndrome (AIDS) 01/2016

Drug/Important Bio-Agent (IBA)

8	Biomarkers (Surrogate Marker)IBA 01/2022 - 03/2013
6	Proteins (Proteins, Gene)FDA Link 01/2022 - 07/2004
5	CarcinogensIBA 01/2021 - 01/2016
4	dactolisibIBA 11/2019 - 01/2017
3	Pharmaceutical PreparationsIBA 01/2022 - 01/2020
2	LY3023414IBA 01/2022 - 01/2017
2	9,10-Dimethyl-1,2-benzanthraceneIBA 01/2021 - 01/2019
2	Phosphatidylinositols (Phosphatidylinositol)IBA 01/2019 - 01/2016
2	sapanisertibIBA 01/2019 - 01/2019
2	Oncogene Proteins (Oncogene Protein)IBA 01/2018 - 01/2016
2	Aldo-Keto ReductasesIBA 12/2017 - 05/2012
2	Chloroquine (Aralen)FDA LinkGeneric 01/2017 - 01/2016
2	Alanine Transaminase (SGPT)IBA 01/2016 - 01/2016
2	salicylhydroxamic acid (SHAM)IBA 01/2016 - 01/2016
2	CytokinesIBA 01/2016 - 03/2013
2	LipidsIBA 04/2014 - 05/2012
2	Small Interfering RNA (siRNA)IBA 04/2014 - 05/2012
2	Transcription Factors (Transcription Factor)IBA 03/2013 - 07/2004
2	EnzymesIBA 05/2012 - 05/2010
2	NF-kappa B (NF-kB)IBA 11/2011 - 07/2004
2	Gastrin-Releasing PeptideIBA 01/2007 - 08/2003
2	Focal Adhesion Protein-Tyrosine KinasesIBA 01/2007 - 08/2003
1	B7-H1 AntigenIBA 01/2022
1	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2022
1	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 01/2022
1	TOR Serine-Threonine KinasesIBA 01/2022
1	MucinsIBA 10/2021
1	DNA (Deoxyribonucleic Acid)IBA 01/2021
1	SiliconIBA 01/2021
1	Estrogens (Estrogen)FDA Link 01/2021
1	Gonadal Steroid Hormones (Sex Hormones)IBA 01/2021
1	IonsIBA 01/2021
1	Antineoplastic Agents (Antineoplastics)IBA 03/2020
1	cabozantinibIBA 03/2020
1	pazopanib FDA Link 03/2020
1	human ERBB2 proteinIBA 01/2020
1	LigandsIBA 01/2020
1	Oxaliplatin (Eloxatin)FDA LinkGeneric 01/2019
1	Mechanistic Target of Rapamycin Complex 1IBA 01/2019
1	Everolimus FDA Link 01/2019
1	Phosphotransferases (Kinase)IBA 01/2019
1	Panitumumab (Vectibix)FDA Link 01/2019
1	ErbB Receptors (EGF Receptor)IBA 12/2018
1	AntibodiesIBA 12/2018
1	SugarsIBA 01/2018
1	Alkaline PhosphataseIBA 01/2018
1	Branched-Chain Amino AcidsIBA 01/2018
1	Glucose (Dextrose)FDA LinkGeneric 01/2018
1	MTOR InhibitorsIBA 01/2017
1	chenodeoxycholate sulfate conjugate (CDCS)IBA 01/2017
1	Proteoglycans (Proteoglycan)IBA 01/2017
1	Versicans (Versican)IBA 01/2017
1	Aspartate Aminotransferases (Aspartate Transaminase)IBA 01/2016
1	CateninsIBA 01/2016
1	theasinensin AIBA 01/2016
1	Transaminases (Aminotransferases)IBA 01/2016
1	anthraceneIBA 01/2016

Therapy/Procedure

9	Therapeutics 01/2022 - 05/2010
5	Precision Medicine 01/2022 - 09/2015
5	Drug Therapy (Chemotherapy) 01/2019 - 05/2010
1	Neoadjuvant Therapy 01/2019
1	Glycemic Control 01/2018
1	Esophagectomy 01/2018
1	Immunotherapy 01/2017
1	Segmental Mastectomy (Lumpectomy) 01/2016
1	Aftercare (After-Treatment) 01/2016
1	Liver Transplantation 01/2016
1	Transplantation 01/2016